Haɗin Alamar Lafiya ta Feline (Abubuwa 5-6)

【 Dalilin gwaji】
Feline pancreatic lipase (fPL): Pancreatic shine mafi girma na biyu mafi girma a cikin jikin dabba (na farko shine hanta), wanda yake a gaban ciki na jiki, ya kasu kashi hagu da dama.Babban aikinsa shi ne ɓoye enzymes masu mahimmanci ga jiki. Pancreatitis ya kasu kashi cikin m pancreatitis da na kullum pancreatitis.Lalacewar da tsohuwar ke haifarwa galibi na ɗan lokaci ne, yayin da na ƙarshe ya bar fibrosis na dindindin da atrophy a cikin yanayin kumburin da ke maimaitawa.Daga cikin su, na kullum pancreatitis lissafin game da 2/3 na cat pancreatitis.
Cholyglycine (CG) ɗaya ne daga cikin sinadarai masu haɗaɗɗiyar cholic acid da aka samu ta hanyar haɗin cholic acid da glycine.Glycocholic acid shine mafi mahimmancin bangaren bile acid a cikin jini lokacin daukar ciki.Lokacin da ƙwayoyin hanta suka lalace, ɗaukar CG ta ƙwayoyin hanta ya ragu, yana haifar da haɓakar abun ciki na CG a cikin jini.A cikin cholestasis, fitar da cholic acid da hanta ya lalace, kuma abun da ke cikin CG ya koma cikin jini yana karuwa, wanda kuma yana kara yawan CG a cikin jini. ta hanyar hanta bayan cin abinci.Hakazalika, cututtukan hanta da toshewar bile duct na iya haifar da ƙayyadaddun ƙididdiga.
Cystatin C yana daya daga cikin sunadarai na cystatin.Mafi mahimmancin aikin ilimin lissafin jiki shine daidaita ayyukan cysteine ​​protease, wanda ke da tasiri mai ƙarfi akan cathepsin B, papain, protease figs, da cathepsin H kuma na saki ta lysosomes.Yana taka muhimmiyar rawa a cikin metabolism na peptides na intracellular da sunadaran, musamman a cikin metabolism na collagen, wanda zai iya hydrolyze wasu prehormones kuma ya saki su cikin kyallen takarda da aka yi niyya don taka rawar nazarin halittu.Ciwon jini na gada tare da amyloidosis cuta ce ta kai tsaye da ke da alaƙa da maye gurbin kwayar halittar cystatin C, wanda zai iya haifar da fashewar jijiyoyin bugun jini, zubar da jini da sauran sakamako masu muni.Koda ita ce kawai wurin da za a share cystatin C mai yawo, kuma samar da cystatin C yana dawwama.Matsayin cystatin C na jini ya dogara ne akan GFR, wanda shine madaidaicin alamar endogenous don nuna canje-canjen GFR.Canje-canjen abun ciki na sauran ruwan jiki shima yana da alaƙa da cututtuka iri-iri.
NT-proBNP (N-terminal pro-brain natriuretic peptide), kuma aka sani da nau'in B-diuretic peptide, wani furotin ne wanda ke ɓoye ta cardiomyocytes a cikin ventricles na zuciya.Lokacin da hawan jini na ventricular ya karu, dilation na ventricular, hypertrophy na myocardial, ko matsa lamba a kan myocardium yana ƙaruwa, madaidaicin NT-proBNP, proBNP (wanda ya ƙunshi amino acid 108), yana ɓoye cikin jini ta hanyar cardiomyocytes.
Cat allergen jimlar IgE (fTIgE): IgE wani nau'i ne na immunoglobulin (Ig) tare da nauyin kwayoyin halitta na 188kD da ƙananan abun ciki a cikin jini.Yawancin lokaci ana amfani da shi don gano alamun rashin lafiyar.Bugu da ƙari, yana iya taimakawa wajen gano cututtuka na parasitic cututtuka da mahara myeloma.1. Rashin lafiyan jiki: lokacin da rashin lafiyan ya faru, yana haifar da haɓakar allergen lgE.Mafi girman rashin lafiyar lgE, mafi girman rashin lafiyar shine.2. Cututtukan parasite: bayan dabbobi sun kamu da ƙwayoyin cuta, allergen lgE kuma na iya ƙaruwa, wanda gabaɗaya yana da alaƙa da rashin lafiyar ɗanɗano da ƙwayoyin cuta ke haifarwa.Bugu da ƙari, kasancewar ciwon daji da aka ruwaito na iya taimakawa wajen haɓaka yawan IgE.
【 Ƙa'idar ganowa】
Wannan samfurin yana amfani da fluorescence immunochromatography don gano ƙididdige abun ciki na fPL/CG/fCysC/fNT-proBNP/fTIgE a cikin jinin cat.Babban ka'idar ita ce membrane na nitrocellulose yana da alamar T da layin C, kuma layin T yana mai rufi da antibody wanda ke gane antigen musamman.Ana fesa kushin daurin da wani mai kyalli nanomaterial mai lakabin antibody b wanda zai iya gane antigen musamman.Maganin rigakafin da ke cikin samfurin yana ɗaure da nanomaterial mai lakabin antibody b don samar da hadaddun, wanda sai ya ɗaure zuwa T-line antibody A don samar da tsarin sanwici.Lokacin da hasken tashin hankali ya haskaka, nanomaterial yana fitar da sigina mai kyalli.Ƙarfin siginar ya kasance daidai da haɗin kai tare da ƙaddamarwar antigen a cikin samfurin.